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History of Stem Cell Research: A Brief Overview

June 2013: Pluripotent Stem Cells Derived from Cloned Human Embryos

❶Since the 19th century, scientists from all over the world have studied stem cells, from plants, to mice, to patients in search of a cure for their diseases.

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July 2013: Human Liver Created from Stem Cells
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Scientists cloned the first mammal through the use of an adult cell. The said clone was born at the Roslin Institute. Moreover, they were able to come to the conclusion that leukemia originates from the same precursor cells as that of normal healthy blood cells. Moreover, this team was able to isolate human embryonic stem cells to create a stem cell line. Given this, scientists now understand the great potential of stem cell research in medicine.

Korean scientists falsified research findings in Their claim was they were able to produce pluripotent stem cells out of unfertilized egg cells. Unfortunately, the Korean scientific community suffered a blow to their credibility in the eyes of the public.

Following this incident, people began to feel more doubtful of scientific facts. Yuan Wang and George A. Daley were able to publish their findings in Their research was able to produce blood cells in mice from their embryonic stem cells. Moreover, their findings became crucial in developing the process of stem cell transplantation. Scientists Yamanaka and Takahashi were able to produce induced pluripotent cells through experimenting with rodents. Furthermore, these induced pluripotent cells are important in stem cell research because these are reprogrammed adult cells made to function like embryonic stem cells.

Moreover, these are pluripotent cells that do not require fertilization. George Daley and his colleagues continued to experiment with mice. Through their research, they managed to create donor-matched embryonic stem cells by means of parthenogenesis. These cells have the potential to replace embryonic stem cells in treatment and research. Moreover, the research team hopes that their findings will contribute to donor-specific transplants.

In using your own cells, the body is less likely to reject the transplant. Three separate research teams were able to create human induced pluripotent cells.

These teams were spearheaded by scientists Yamanaka, Thomson, and Daley. A post shared by Barack Obama barackobama on Oct 11, at 4: In , then US President Barack Obama allowed for the revision of some of the restrictions on research involving embryonic stem cells. It is through this executive order that stem cell research was able to get more funding and thus be capable of moving forward. Following this, we can expect more groundbreaking developments in the years to come.

Understanding the history of stem cell research is important in the understanding of the latest developments in biomedical technology. Hopefully, given the increase in funding available to stem cell researchers, progress will be consistent and groundbreaking in years to come.

Given this, we might just be on the cusp of finding solutions to conditions currently incurable. What do you think of stem cell research? Please share your thoughts with us in the comments below! This copyrighted material may not be republished without express permission. The information presented here is for general educational purposes only.

History of Stem Cell Research: However, the bill is quickly vetoed by President Bush. The House votes in favor of the bill, but the two-thirds majority needed to override the veto is not reached. The House also passes the Senate's version of the bill Again, the bill is vetoed by President Bush, and again Congress cannot override the veto. A group of plaintiffs led by adult stem cell scientists James Sherley, M. The case was brought up against Kathleen Sebelius, the U.

Secretary of Health and Human Services at that time. Court of Appeals for the D. Circuit] reasoning and conclusions, must find that defendants reasonably interpreted the Dickey-Wicker Amendment to permit funding for human embryonic stem cell research because such research is not 'research in which a human embryo or embryos are destroyed' That policy question is not answered by any congressional law, and it has fallen on three presidential administrations to provide an answer.

For all three such administrations, Democratic and Republican, the answer has been to permit federal funding. They have differed only as to the path forward. See the full text of the ruling here. Researchers at Cedars-Sinai Medical Center and Johns Hopkins University publish results from a clinical trial in which adult stem cells were extracted from patients following a heart attack.

In the first demonstrated case of therapeutic regeneration, the treatment decreases scarring and leads to regrowth of heart tissue.

In a decision favorable to proponents of ES cell research, the U. Sebelius , thereby upholding the previous ruling of the D. By removing the DNA from an egg cell and replacing it with genetic material from a skin cell, scientists create stem cells that can be programmed into becoming many different cell types, including the contracting cardiomyocytes that make up our heart muscle.

Nuclear transfer NT -ES cells hold great promise for regenerative medicine because the resulting stem cells are a genetic match to the skin cell donor. An FDA-approved clinical trial finds that treatment with ES cells improves sight in over half of 18 patients suffering from macular degeneration.

History of Stem Cell Research | Understanding the Timeline

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The information used to compile this Stem Cell Research Timeline comes from many different sources, including the National Institutes of Health. A useful list of links to other stem cell research timelines from around the Web can be found at the bottom of this page.

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This timeline takes you through the ups and downs of the stem cell rollercoaster. , Mouse beginnings Martin Evans of Cardiff University, UK, then at the University of Cambridge, is first to identify embryonic stem cells – in mice.

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History of Stem Cell Research — A Timeline Wrights/Giemsa stained human embryonic stem cell (hESC) colony on murine embryonic fibroblast feeder cells. The colony contains roughly individual hESCs. From early fetal tissue research to the first successful human treatments, this timeline documents the progress in stem cell science, and the policies that have impeded or promoted it. The stories of research involving human embryonic stem cells and the policy governing that work are intertwined and stretch back into the mids.

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Stem cells have been used in medicine since the ’s when bone marrow transplants were first used to treat leukemia. Congressional involvement in stem cell policy started as early as The first major amendment related to the use of federal funds for research involving embryonic stem (ES) cells occurred in The history of stem cell research, a timeline made with Timetoast's free interactive timeline making software.